| ncRNA name | mmu-miR-188-5p |
| ncRNA Category | miRNA |
| Disease name | choroidal neovascularization (CNV) |
| Species | Mus musculus |
| Tissues/Cell_line | bone marrow-derived cells (BMCs), mesenchymal stem cells (MSCs) |
| Methods | qRT-PCR, fluorescence in situ hybridization (FISH), luciferase reporter assay, Western blot, immunofluorescent staining, transfection, tube formation assay |
| Expression pattern | down-regulated |
| Functional description | miR-188-5p regulates the contribution of BMCs to CNV development by targeting MMP-2/13-mediated extracellular matrix degeneration, and miR-188-5p serves as a therapeutic target to treat CNV-related diseases. |
| PubMed ID | 29908885 |
| Year | 2018 |
| Title | MicroRNA-188-5p regulates contribution of bone marrow-derived cells to choroidal neovascularization development by targeting MMP-2/13. |
| Drug-related ncRNA | NO |
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